The Andrology Laboratory at Pooyesh Fertility Clinic, Isfahan Health City Care, is staffed by experienced professionals in biology, genetics, and laboratory sciences. Equipped with advanced technology and adhering to WHO standards, the laboratory provides specialized diagnostic and therapeutic services related to sperm health.

Main Sections of the Laboratory:

1. Sperm Diagnostic Section:

This section evaluates sperm health and quality using precise scientific methods and advanced equipment. Key facilities include:

• Dedicated and fully equipped sample collection rooms for couples
• Semen analysis using CASA (Computer-Assisted Sperm Analysis)
• Evaluates sperm count, motility, and morphology
• Sperm DNA quality assessment using SCSA (Sperm Chromatin Structure Assay)
• Flow cytometry is used to evaluate DNA damage and genetic quality

SCSA is recommended or essential for individuals who:

• Work in high-risk occupations
• Have low sperm motility
• Are exposed to chemicals
• Maintain unhealthy lifestyles (smoking, stress, poor nutrition, etc.)

2. Sperm Therapeutic Section:

This section prepares sperm samples for assisted reproductive technologies (ART) including: IVF, ICSI, IUI, gender selection, and preimplantation genetic testing (PGT).

Sperm preparation techniques include:

• Density Gradient Centrifugation (DGC)
• Microfluidic Sperm Sorting (MF)
• Zeta Potential Sperm Selection (ZETA)
• Hypo-Osmotic Swelling Test (HOST)
• Swim-Up Method
• Swim-Down Method

Testicular Tissue Sampling:

If sperm is not found in semen, testicular tissue sampling may be performed under urologist guidance using:

• FNA (Fine Needle Aspiration)
• Micro-TESE (Microsurgical Sperm Extraction)
  These samples are processed in the laboratory with specialized techniques.

Sperm Cryopreservation:

The laboratory offers sperm freezing under controlled conditions for:

• Men preparing for chemotherapy or other high-risk treatments
• Individuals with suboptimal sperm quality
• Couples wishing to use sperm at a later time
  Frozen samples are securely stored and ready for future use.

Location: Phase 1, Isfahan Health Care City, Pooyesh Fertility Clinic
Head of the department: Ms. Safura Asgharzadeh
Technical Supervisor: Dr. Zahra Darmishoon Nejad